The purpose of this study is to determine the attitudes of healthcare professionals towards CoronaVac and BioNTech vaccines applied in Turkey without the completion of phase 3 studies and to contribute to the policies that will be developed for the vaccine. The data in the study were collected between 01.03.2021 and 31.03.2021. The population consists of healthcare workers working in primary and secondary healthcare institutions in Samsun (N= 11.840). In determining the sample size, the unknown prevalence was taken as 50% and the margin of error as 3% by using the Open Epi Calculator program and it was determined as 979 with an error level of 0.05 and a power of 80%. Two forms were used for data collection namely Personal Introductory Information Form and Vaccination Attitude Scale. The data were evaluated with regression model and descriptive analysis such as number and percentage. The average age of the participants in the study was 38.33 ± 8.852, the average working year was 14.99 ± 8.920, 61.7%. 79% of the healthcare professionals were vaccinated for Covid 19, and all of them were vaccinated with CoronaVac vaccine. The vaccine acceptance average for CoronaVac vaccine is 3.81 ± 0.870, and the vaccine acceptance average for BioNTech vaccine is 3.76 ± 0.778. The attitude of those with more education and working years is better than others towards the BioNTech vaccine. An important finding of the study is that 79% of the healthcare workers in the research group were vaccinated; in other words, 21% of them corresponding to one out of five people were not vaccinated. The second important finding of the study is that those with higher education and more working years have a better attitude towards BioNTech vaccine than others.