Phyllodes Tumor of The Breast: Histopathological and Clinical Results of 13 Cases

Author:

Number of pages: 234-238
Year-Number: 2021-Volum: 3, Issue: 3

Abstract

Keywords

Abstract

Phyllodes tumors (PT) are biphasic tumors originating from cleft-like spaces lined by epithelial cells and the hypercellular stroma. PT is a very rare tumor of the breast. The World Health Organization (WHO) classifies it as benign, borderline, or malignant. In this research, we aimed to describe the radiological, pathological, and clinical results of patients, who were admitted to our hospital and diagnosed with PT and evaluate them in the light of the literature. A total of 13 PT patients diagnosed in the pathology laboratory of Konya Training and Research Hospital between January 2010 and December 2019 were retrospectively analyzed. The mean age of the patients was 42.69 years (range, 18-64). The tumor location was the right breast in 4 (30.7%) patients and the left breast in 9 (69.3%) patients. Of the malignant PT, 1 (20%) was located in the right breast and 4 (80%) were located in the left breast. Of the patients, 5 (38.5%) were diagnosed with benign PT, 3 (23%) with borderline PT, and 5 (38.5%) were diagnosed with malignant PT. The mean tumor size was 7.7 cm, and the diameter of each of the malignant PT was larger than 7.7 cm, with a mean diameter of 12.9 cm. PT should be correctly identified at initial diagnosis and treated effectively, as the risk of recurrence is high. To develop new treatment modalities, we should especially understand malignant lesions well, and also attach importance to patient education and awareness.

Keywords