There is no consensus on the treatment of the IGM. It is a chronic and self limiting bening disease and the management of the disase is based on the clinical syptoms of the patients. Treatment modalities differs among patients from follow-up to surgical resection of the tissue. In this study, we compared azathioprine treatment to surgical treatment. In this study, between january 2008 and april 2016 at uludağ university medicine faculty deparmant of general surgery, unit of breast surgery; 99 patients who show signs of granulomatous mastitis and proved histopat logical methods were enrolled. They were allocated in two groups. First group contains 26 patients treated with azathioprine and undergone no surgery while second group contains 73 patients are surgically treated. All the patients were female and 96 people were married while 3 people were unmarried. İn our study, relapces are seen at % 23.80 (n=19) of 80 patients with no surgery, %58.30 (n=7) of 12 patients with abscess drainage for once, %14.1 (n=1) of 7 patients with abscess drainge for more then once. According to relapce rate, statistical difference were found between groups. Relapce rate were higher at the group with drainage of abscess for once than the group with no surgery. In our study, we conclude that medical therapy is effective for disease treatment but long term therapy is necessary.