The levels of depression and hopelessness among emergency service workers increase, if the necessary measures are not taken in emergency departments that have high levels of workload and stress. In this study, we aimed to investigate the levels of depression and hopelessness among emergency service workers and the factors affecting these levels. This study included a total of 80 volunteer healthcare employees working in the emergency service of our hospital. Beck depression and Beck hopelessness levels of the participants were measured both before and after their shifts. Additionally, participants were classified according to the economic level and the correlation between economic level, depression and hopelessness scales was investigated. Though Beck depression points were lowest before shift, nurses-health officers were the group with highest increase in depression after shift (p=0.004). Physicians were the group with highest Beck hopelessness levels before and after shift. In the group with highest economic level, there was a 30% increase in the severity levels of hopelessness both before and after shift. Physicians were the group with highest hopelessness levels among emergency service health personnel. Additionally, the group of emergency service employees with highest economic level were had higher levels of depression and hopelessness compared to the other groups.