Evaluation of the Relationship Between Epicardial Fat Tissue Area and Coronary Atherosclerosis

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Number of pages : 70-75

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Abstract

In our study, it was aimed to investigating the correlation between the quantity of epicardial adipose tissue with the development of coronary atherosclerosis and coronary artery disease. In this retrospective research we used Cardiac CT Angiography images of 40 patients (age range 23-80, 30 males, 10 females). The area of epicardial adipose tissue and total calcium score values were measured. All the patients were examined for obstructive coronary artery disease. Epicardial adipose tissue areas were measured in the level of the left main coronary artery. The data obtained were analyzed with SPSS program. 13 patients were found positive for Ca score and coronary stenosis was dedected in 18 patients. There is independent correlation between the area of epicardial adipose tissue and; age and total calcium score (age: p=0.003, total calcium score: p=0.020). Based on results and statiscal analysis, the area of epicardial adipose tissue was found statistically significant among the patients, who have positive Ca score (p=0.017) and coronary artery stenosis (p=0.019). As result, based on the outcomes of this study, it can be concluded that the increase of epicardial adipose tissue has significant impact on occurence of coronary artery stenosis and calcific-atherosclerotic changes. Also, for the calculation of epicardial adipose tissue quantity, the measurement of cross section area from left main coronary artery surface is a good alternative to have an easiness of measurement as well as total volume of epicardial adipose tissue.

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