We aim to evaluate the effects of prolonged use of IUD (Intrauterine device) in endometrium curettage materi-als and the relationship between the use of IUD and eosinophils. Between 2018 and 2020, the pathology preparations of 38 patients who applied to our hospital with abnormal uterine bleeding and had IUD, and 30 patients with abnormal uterine bleeding alone as the control group were examined by a single pathologist. Histopathological diagnosis in the curettage materials with a light microscope, eosinophil leukocyte, neutrophil, plasmocyte counts, and accompanying histopathologi-cal findings were re-evaluated in 10XHMF (High magnification fields) in compact areas without destruction findings. In our study, the eosinophil presence rate of 38 patients using IUD was 81%. The average duration for IUD use in these patients was seven years. The average duration of IUD use for seven patients who had no eosinophils detected was two years. The average duration of IUD use for 31 patients with eosinophils was 7.5 years. In the control group patients who were not using IUD with abnormal uterine bleeding, the eosinophil presence rate was found to be 36%. The use of IUD does not always cause an increase in eosinophils in the endometrium but is accompanied by high rates. However, we can say that the number of eosinophils increases as the IUD carrying time increases. It should be kept in mind that eosinophil leukocytes, monitored by gynecopathologists in curettage materials, may be associated with prolonged IUD use.